The third year of iPC project has started and in order to present the current work that each consortium partner is developing, we asked them to summarize the processes that are being done behind the project. This week we present the Ghent University where prof. Pieter Mestdagh (PhD) and the team explains the current work that they are developing within iPC:
“Our role in the IPC project is to build computational deconvolution models for various pediatric tumor types. A computational deconvolution model enables us to determine the cellular composition of a tumor biopsy using nothing more than the bulk RNA-sequencing profile of that biopsy. The abundance of certain cell types can be used for tumor subtype classification or to predict response to certain therapies.”
